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  • Title: Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists.
    Author: Xin Z, Zhao H, Serby MD, Liu B, Schaefer VG, Falls DH, Kaszubska W, Colins CA, Sham HL, Liu G.
    Journal: Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1201-4. PubMed ID: 15686942.
    Abstract:
    A series of isoxazole carboxamide derivatives has been developed as potent ghrelin receptor antagonists. The synthesis and structure-activity relationship (SAR) are described.
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