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  • Title: [ASCUS of metaplastic type. Cyto-histopathological correlations].
    Author: Teleman S, Anton C, Socolov D, Ungureanu C, Danciu M, Mihailovici MS.
    Journal: Rev Med Chir Soc Med Nat Iasi; 2004; 108(1):85-9. PubMed ID: 15688762.
    Abstract:
    We evaluated the cytopathological changes and the prognostic significance of atypical squamous metaplastic cells in cervical smears. 50 ASCUS cases were divided in two groups: 25 cases in different settings and 25 of metaplastic type. All cases were re-evaluated after 6 months and when necessary, verified by biopsy. The second cytological diagnosis was: group I--13 normal, 2 LSIL, 40 ASCUS; group II--6 normal, 2 LSIL, 2 HSIL and 15 ASCUS. The HPV was positive in 5 cases in group I and in 9 cases in group II. In ASCUS persistent cases the biopsy revealed: in group I--3 CIN 1 and 1 CIN 2 cases; in group II--1 CIN 1, 2 CIN II, 2 CIN III and one case of microinvasive carcinoma. In conclusion, atypical metaplastic cells are more frequently involved in serious cervical lesions.
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