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  • Title: [New methyl-quinoxaline derivatives with antimicrobial activity].
    Author: Ungureanu M, Poiată A, Tuchiluş C.
    Journal: Rev Med Chir Soc Med Nat Iasi; 2004; 108(1):181-4. PubMed ID: 15688781.
    Abstract:
    This paper presents the synthesis of six new quinoxaline derivatives cycloadditions products of N-monoxide and N,N'-dioxide of 6-methyl-quinoxaline. The chemical structure of new azabicyclic products was confirmed by C, H, N elemental analysis and spectral analysis (IR and RMN). We have tested the antimicrobial activity of the new synthesized azabicyclic derivatives by the diffusimetric method. The assay was made on the seven microorganisms, gram-positive and gram-negative bacteria. The results show that the new compounds are more active against the gram-positive bacteria and Candida albicans.
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