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  • Title: [Rosai-Dorfman syndrome. On the differential diagnosis of lymph node swelling].
    Author: Philipp A, Laszig R, Werner M.
    Journal: HNO; 1992 Feb; 40(2):56-8. PubMed ID: 1568888.
    Abstract:
    The Rosai-Dorfman syndrome is a benign disease, one of its commonest affected sites being the cervical lymph nodes. This disease should be considered in the differential diagnosis of a cervical lymphadenopathy. The syndrome often begins with a chronic rhinitis, and is accompanied by sinusitis, tonsillitis or pharyngitis; blood tests indicate chronic infection. The pathogenesis of the disease is still unknown but may include infection or an abnormal autoimmune reaction. The diagnosis is established by the findings of characteristic histiocytes with haemophagocytosis. We report a female patient with persistent cervical lymph node swelling resistant to treatment. The cause was proved by histology to be a Rosai-Dorfman syndrome.
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