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  • Title: Sclerosing epitheloid fibrosarcoma. A report of two cases.
    Author: Bezić J, Tomić S, Glavina-Durdov M, Alfirević D, Samija I, Krizanac S.
    Journal: Pathologica; 2004 Oct; 96(5):433-5. PubMed ID: 15688980.
    Abstract:
    Sclerosing epitheloid fibrosarcoma is a rare, histologically well-defined member of adult fibrosarcoma group of soft tissue tumors. Its main histological features are nests and cords of rounded tumor cells surrounded by hyalinized collagenous stroma. Epitheloid appearance with marked sclerosis and infiltrating growth pattern, along with occasional immunohistochemical positivity for epithelial markers may be highly suggestive of infiltrating carcinoma. Despite of bland cytological features clinical course is often protracted with a high local recurrence rate and late metastases. In this report, we present histopathological characteristics of two cases of sclerosing epitheloid fibrosarcoma, together with their clinical presentation, follow-up information and differential diagnosis.
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