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PUBMED FOR HANDHELDS

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  • Title: Use of lithium for treatment of estrogen-induced bone marrow hypoplasia in a dog.
    Author: Hall EJ.
    Journal: J Am Vet Med Assoc; 1992 Mar 15; 200(6):814-6. PubMed ID: 1568928.
    Abstract:
    Marrow hypoplasia and consequent pancytopenia caused by simultaneous administration of estradiol cyclopentylpropionate and diethylstilbestrol were diagnosed in a 6-year-old Old English Sheep-dog. The dog was treated with lithium carbonate (11 mg/kg of body weight, PO, q 12 h) for 6 weeks. Despite the generally grave prognosis associated with estrogen toxicosis, lithium treatment was apparently successful in inducing regeneration of the bone marrow. Side effects of lithium treatment were not noticed.
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