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  • Title: Protocol biopsies after kidney transplantation.
    Author: Böhmig GA, Regele H, Hörl WH.
    Journal: Transpl Int; 2005 Feb; 18(2):131-9. PubMed ID: 15691264.
    Abstract:
    Numerous studies have investigated features of allograft injury in renal biopsies obtained in stable kidney transplants. Evaluation of protocol biopsies has revealed a considerably high prevalence of subclinical acute rejection (SAR) and chronic allograft nephropathy (CAN) already in early phases after transplantation. The meanwhile well-established association of SAR and CAN in protocol biopsy with long-term allograft failure and the finding of superior allograft outcome after treatment of SAR in a randomized prospective study may point to clinical relevance of this procedure. In this review, potential benefits and risks associated with kidney allograft biopsy in stable renal transplant recipients are discussed.
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