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  • Title: Leukocyte adhesion: what's the catch?
    Author: Hammer DA.
    Journal: Curr Biol; 2005 Feb 08; 15(3):R96-9. PubMed ID: 15694300.
    Abstract:
    A recent study shows that the leukocyte adhesion molecules known as selectins form 'catch' bonds, the dissociation rate of which decreases with increasing applied force. The ability of selectins to switch between catch and slip bonds, where dissociation increases with force, can explain the shear threshold effect, in which leukocyte adhesion goes through a maximum with increasing shear rate.
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