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  • Title: Multi-adaptive filtering technique for surface somatosensory evoked potentials processing.
    Author: Lam BS, Hu Y, Lu WW, Luk KD, Chang CQ, Qiu W, Chan FH.
    Journal: Med Eng Phys; 2005 Apr; 27(3):257-66. PubMed ID: 15694610.
    Abstract:
    Somatosensory evoked potential (SEP) testing has been widely applied to diagnosis of various neurological disorders. However, SEP recorded using surface electrodes is buried in noises, which makes the signal-to-noise ratio (SNR) very poor. Conventional averaging method usually requires up to thousands of raw SEP input trials to increase the SNR so that an identifiable waveform can be produced for latency and amplitude measurement. In this study, a multi-adaptive filtering (MAF) technique, emerging from the combination of well-developed adaptive noise canceller and adaptive signal enhancer, is introduced for fast and accurate surface SEP extraction. The MAF technique first processes the raw surface recorded SEP by the Canceller with a reference noise channel of background noise for adaptive subtraction before entering the Enhancer. The MAF was verified by filtering simulated SEP signals in which electroencephalography and Gaussian noise of different SNRs were added. It was found that the MAF could effectively suppress the noise and enhance the SEP components such that the SNR of the SEP is improved. Results showed that MAF with 50 input trials could provide similar performance in SEP detection to those extracted by the conventional averaging method with 1000 trials even at an SNR of -20 dB.
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