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  • Title: [Calcification of the falx cerebri. A pathognomonic symptom of Gorlin-Goltz syndrome].
    Author: Lambrecht JT, Stübinger S, Siewert B, Härle F.
    Journal: HNO; 2005 Aug; 53(8):701-4, 706. PubMed ID: 15696312.
    Abstract:
    BACKGROUND: Gorlin-Goltz syndrome is an autosomal dominant disorder with variable penetration characterized primarily by keratocysts of the jaws, multiple basal cell carcinomas, skeletal abnormalities and intracranial calcifications. METHOD: In this study, 4787 radiographs with occipitomental x-rays from the hospital archives for oral and maxillofacial surgery of the Christian Albrechts University Kiel were examined for calcifications in the area of the falx cerebri. RESULTS: Four characteristic alterations in the falx cerebri could be assigned to four groups of structures. Those in group 4 could be found only within Gorlin-Goltz syndrome patients, and differed significantly in form and extent from the remaining three groups. CONCLUSION: The plurilamellar appearance of this group could be rated as a pathognomonic symptom of the Gorlin-Goltz syndrome.
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