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  • Title: Congenital melanotic macules and Sebaceous Choristoma arising on the tongue of a newborn: epidermal choristoma?
    Author: Azorin D, Enriquez de Salamanca J, de Prada I, Colmenero I, Gonzalez Mediero I.
    Journal: J Cutan Pathol; 2005 Mar; 32(3):251-3. PubMed ID: 15701089.
    Abstract:
    Oral hyperpigmentation is a common event in older individuals, however, is exceptional in neonates (congenital melanotic macules). Conversely, 70-80% of people have sebaceous glands in the oral mucosa, with the tongue representing an ectopic location and termed sebaceous choristoma by some authors. We report a case that fulfills both conditions in a tongue lesion. A 1-month-old boy presented with a pigmented macula on his tongue noted at birth. An excisional biopsy was performed showing a lesion lined by an epidermal-like epithelium with basal pigmentation, under which, sebaceous glands, abortive hair follicles and ductal structures mimicking apocrine glands were found. Seven cases of congenital melanotic macules of the tongue have been reported, however, none of them showed sebaceous glands under the lesion. Furthermore, there has not been a reported case of sebaceous choristoma of the tongue present at birth. We present a case that shares clinical and histological features of both conditions and propose the name 'epidermal choristoma'.
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