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  • Title: CO2 as a distending medium for gastric and small bowel MRI: a feasibility study.
    Author: Lomas DJ, Habib SH, Joubert IJ, Sala E, Graves MJ.
    Journal: Eur Radiol; 2005 Apr; 15(4):672-6. PubMed ID: 15703949.
    Abstract:
    This work evaluates carbon dioxide as a contrast medium for magnetic resonance imaging of the stomach and small bowel. Twelve healthy volunteers underwent rapid magnetic resonance imaging after oral administration of a carbon dioxide generating agent using a combination of breath-hold and interactive fluoroscopic imaging during breathing. Diagnostic-quality images were obtained in 100% of cases for the stomach and in 92, 75, 67 and 42% of cases for the duodenal segments 1-4, respectively. Visualisation of the jejunum and ileum proved unacceptable for clinical use and anti-peristaltic agents did not significantly influence the results. Further development of fast imaging and magnetic resonance interactive fluoroscopic methods may allow the use of carbon dioxide as a contrast medium for clinical imaging of the stomach and duodenum.
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