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  • Title: Crystalloid deposits in the kidney.
    Author: Keller LS, Faull RJ, Smith P, Swift J, Bannister KM, Otto S, Peh CA.
    Journal: Nephrology (Carlton); 2005 Feb; 10(1):81-3. PubMed ID: 15705186.
    Abstract:
    Light chain-producing lymphoproliferative disorders such as multiple myeloma are frequently complicated by renal impairment. Typically, the renal biopsy of a patient with renal failure caused by multiple myeloma shows cast nephropathy, but occasionally crystals may be seen. We describe the case of a patient with acute renal failure caused by multiple myeloma in which, on renal and bone marrow biopsy, there were widespread crystalloid deposits. Crystalloid nephropathy is a very rare condition associated with multiple myeloma and other light chain-secreting disorders. An underlying lymphoproliferative disorder should be considered in the differential diagnosis if crystalloid deposits are seen on a renal or other tissue biopsy.
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