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  • Title: [The effect of huanglian jiedu tang on Alzheimer's disease and its influence on cytokines].
    Author: Fang Q, Zhan XP, Mo JL, Sun M.
    Journal: Zhongguo Zhong Yao Za Zhi; 2004 Jun; 29(6):575-8. PubMed ID: 15706928.
    Abstract:
    OBJECTIVE: To investigate the effect of huanglian jiedu tang on Alzheimer' s disease, and its influence on cytokines. METHOD: AD rats models were made by A beta injection, and then water-maze tests were made to investigate the study and memory ability. TNF-alpha, INF-gamma and IL-2 were examined by ELISA. After treatment with huanglian jiedu tang, the rats were evaluated again. RESULT: After A beta injection, the study and memory ability of the rats was decreased. By the treatment with huanglian jiedu tang, it was improved (P < 0.01); TNF-alpha, INF-gamma and IL-2 levels of AD rats were higher than those in control group (P < 0.01); after treatment the levels came down (P < 0.01). CONCLUSION: Huanglian jiedu tang can improve the study and memory ability of AD rats by changing their immune state.
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