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  • Title: Potential mediators of cognitive-behavioral therapy for adolescents with comorbid major depression and conduct disorder.
    Author: Kaufman NK, Rohde P, Seeley JR, Clarke GN, Stice E.
    Journal: J Consult Clin Psychol; 2005 Feb; 73(1):38-46. PubMed ID: 15709830.
    Abstract:
    Several possible mediators of a group cognitive-behavioral therapy (CBT) for depressed adolescents were examined. Six measures specific to CBT (e.g., negative cognitions, engagement in pleasurable activities) and 2 nonspecific measures (therapeutic alliance, group cohesion) were examined in 93 adolescents with comorbid major depressive disorder and conduct disorder who were randomly assigned to the Adolescent Coping With Depression (CWD-A) course or a life skills control condition. Change on the Automatic Thoughts Questionnaire (S. D. Hollon & P. C. Kendall, 1980) appeared to mediate treatment effects on depressive symptoms. Therapeutic alliance by the 3rd session was higher among the CWD-A participants but did not predict reductions in depressive symptoms. Findings suggest that reducing negative thinking may be the primary mechanism through which the CWD-A intervention reduces depression.
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