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  • Title: Effect of a single dose of rituximab in chronic immune thrombocytopenic purpura in childhood.
    Author: Taube T, Schmid H, Reinhard H, von Stackelberg A, Overberg US.
    Journal: Haematologica; 2005 Feb; 90(2):281-3. PubMed ID: 15710595.
    Abstract:
    Twenty-two children with immune thrombocytopenic purpura (ITP) with long-lasting thrombocytopenia, adversely affecting their quality of life, were treated with a reduced rituximab regimen in order to eliminate B cells producing anti-platelet antibody. A single dose of rituximab resulted in a response rate similar to that reported for cases in which 4 doses of rituximab were used.
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