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  • Title: Zygomycosis after prolonged use of voriconazole in immunocompromised patients with hematologic disease: attention required.
    Author: Vigouroux S, Morin O, Moreau P, Méchinaud F, Morineau N, Mahé B, Chevallier P, Guillaume T, Dubruille V, Harousseau JL, Milpied N.
    Journal: Clin Infect Dis; 2005 Feb 15; 40(4):e35-7. PubMed ID: 15712069.
    Abstract:
    We describe 4 cases of zygomycosis that occurred after prolonged use of voriconazole in severely immunocompromised patients with hematologic disease. An invasive infection was present in 3 patients who died soon after the diagnosis at 12, 13, and 45 days. Physicians should be mindful of this potential risk after treatment with voriconazole.
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