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  • Title: [In vivo 31-phosphorus MR spectroscopy of the calf musculature in arterial occlusive diseases].
    Author: Melchert UH, Brinkmann G, Förger K, Gleim M, Wunsch-Binder F, Maier C, Zick G.
    Journal: Rofo; 1992 Apr; 156(4):346-52. PubMed ID: 1571516.
    Abstract:
    Muscle metabolism was measured in 7 patients with arterial occlusive disease and symptoms of intermittent claudication both before and after percutaneous vascular neurolysis by means of dynamic 31P-MR spectroscopy. Phosphorus spectra of the involved calf muscles were determined before, during and after defined treadmill exercise. In addition to pH values the phosphocreatine content was measured during activity and recovery phases. There was close correlation in these patients between the increase in claudication distance and more rapid regeneration of phosphocreatine following neurolysis. However, none of the patients achieved normal values of phosphate metabolism. By means of the non-invasive 31P-MR spectroscopy it was possible for the first time to demonstrate the biochemical changes associated with neurolytic lumbar sympathetic blockade.
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