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  • Title: [Enhanced absorption of breviscapine photosomes in small intestine of rats].
    Author: Tang XQ, Yang XL.
    Journal: Zhongguo Zhong Yao Za Zhi; 2005 Feb; 30(3):222-5. PubMed ID: 15719646.
    Abstract:
    OBJECTIVE: To investigate whether the absorption of breviscapine can be enhanced by using breviscapine photosomes. METHOD: Testing the uptake and intestinal permeability of breviscapine powder and breviscapine photosomes by using intestine perfusion technique and reverted gut sac method. RESULT: The uptake and permeability coefficient of breviscapine were increased in photosomes. The absorption process obeyed the Fick's law in the range of 0-100 microg x mL(-1). CONCLUSION: The absorption breviscapine photosomes is enhanced by increasing the permeability through a passive mechanism.
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