These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Specific features of the erythroid hemopoietic stem in CBA/CaLac mice with neuroses demonstrating good and poor learning capacities.
    Author: Pershina OV, Skurikhin EG, Stavrova LA, Suslov NI, Dygai AM.
    Journal: Bull Exp Biol Med; 2004 Nov; 138(5):442-6. PubMed ID: 15723121.
    Abstract:
    We studied changes in the erythroid hemopoietic stem in CBA/CaLac mice with experimental neuroses demonstrating good and poor learning capacities (conflict situation and paradoxical sleep deprivation followed by training in a 3-arm T-maze). The animals with different learning capacities exhibited pronounced hyperplasia of the erythroid hemopoietic stem in response to neurosis. Activation of the erythron in good learners was related to acceleration of division and maturation of erythroid precursors and enhanced formation of cell complexes containing central macrophage. In poor learners hyperplasia of the erythroid hemopoietic stem under conditions of conflict situation manifested in activation of proliferation and differentiation (against the background of decreased count of erythroid and mixed complexes in the bone marrow), while after paradoxical sleep deprivation followed by T-maze training this hyperplasia was associated with increased formation of additional hemopoietic islets (against the background of desynchronization of division and maturation of erythroid precursor cells).
    [Abstract] [Full Text] [Related] [New Search]