These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: TorD, an essential chaperone for TorA molybdoenzyme maturation at high temperature.
    Author: Genest O, Ilbert M, Méjean V, Iobbi-Nivol C.
    Journal: J Biol Chem; 2005 Apr 22; 280(16):15644-8. PubMed ID: 15723832.
    Abstract:
    TorD has been recognized as an accessory protein that improves maturation of TorA, the molybdenum cofactor-containing trimethylamine oxide reductase of Escherichia coli. In this study, we show that at 42 degrees C and in the absence of TorD TorA is poorly matured and almost completely degraded. Strikingly, TorD restores TorA maturation to the same level whatever the growth temperature. In vitro experiments in which apoTorA was incubated with or without TorD at various temperatures confirm that TorD is an essential chaperone for TorA at elevated temperatures preventing apoTorA mis-folding before cofactor insertion.
    [Abstract] [Full Text] [Related] [New Search]