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  • Title: [Studies on dissolution rate in vitro of silymarin dropping pill].
    Author: Sun X, Qiu MF, Li SS, Wang JX, Shen Q, Jia W.
    Journal: Zhongguo Zhong Yao Za Zhi; 2005 Feb; 30(4):263-5. PubMed ID: 15724400.
    Abstract:
    OBJECTIVE: To test the dissolution rate of silymarin dropping pill as well as to be compared with other three commercial products of the silymarin. METHOD: By UV spectrophotometry, we studied the dissolution conditions of silymarin dropping pill and compared its dissolution rate with Yiganling tablets (film-coating, sugar-coating) and Legalon capsule which are available in the market. RESULT: The dissolution parameters T50 and Td of silymarin dropping pill, Yiganling tablet (film-coating), Yiganling tablet (sugar-coating) and Legalon capsule are 6.78, 9.85 min, 51.01, 73.78 min, 74.35, 86.97 min and 53.10, 72.65 min. CONCLUSION: The dissolution rate of silymarin dropping pill is superior to that of two kinds of Yiganling tablets and Legalon capsule.
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