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  • Title: Rapid and efficient synthesis of 1,2,4-oxadiazoles utilizing polymer-supported reagents under microwave heating.
    Author: Wang Y, Miller RL, Sauer DR, Djuric SW.
    Journal: Org Lett; 2005 Mar 03; 7(5):925-8. PubMed ID: 15727476.
    Abstract:
    1,2,4-Oxadiazoles can be rapidly and efficiently synthesized from a variety of readily available carboxylic acids and amidoximes using either method A or method B. The use of commercially available polymer-supported reagents combined with microwave heating resulted in high yields and purities of the product 1,2,4-oxadiazoles in an expeditious manner. [structure: see text]
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