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  • Title: Disequilibrium in distribution of resistance mutations among Mycobacterium tuberculosis Beijing and non-Beijing strains isolated from patients in Germany.
    Author: Hillemann D, Kubica T, Rüsch-Gerdes S, Niemann S.
    Journal: Antimicrob Agents Chemother; 2005 Mar; 49(3):1229-31. PubMed ID: 15728936.
    Abstract:
    Genotypic analysis of 103 multidrug-resistant Mycobacterium tuberculosis strains isolated in Germany in 2001 revealed that mutations in codon 531 (75.7%) of the rpoB gene and codon 315 (88.4%) of the katG gene are most frequent. Beijing genotype strains (60.2% of all isolates) displayed a different distribution of resistance mutations than non-Beijing strains.
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