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  • Title: Novel bromotyrosine derivatives that inhibit growth of the fish pathogenic bacterium Aeromonas hydrophila, from a marine sponge Hexadella sp.
    Author: Matsunaga S, Kobayashi H, van Soest RW, Fusetani N.
    Journal: J Org Chem; 2005 Mar 04; 70(5):1893-6. PubMed ID: 15730316.
    Abstract:
    Three new bromotyrosine derivatives, 11-N-methylmoloka'iamine (1), 11-N-cyano-11-N-methylmoloka'iamine (2), and kuchinoenamine (3), were isolated as antibacterial constituents from a marine sponge Hexadella sp. Their structures were elucidated on the basis of spectral and chemical methods. They exhibited moderate antibacterial activity against the fish pathogenic bacterium Aeromonas hydrophila.
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