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  • Title: [Usefulness of chemotherapy associated with surgery in the management of nontuberculous mycobacterial adenitis].
    Author: Sanz Santaeufemia FJ, Ramos Amador JT, Giangaspro E, Sánchez Granados JM, Palenque E, González Tomé MI.
    Journal: An Pediatr (Barc); 2005 Mar; 62(3):280-5. PubMed ID: 15737291.
    Abstract:
    BACKGROUND: In recent years, lymphadenitis caused by atypical mycobacteria (also called nontuberculous mycobacteria [NTMB] or, more recently, environmental) have played a significant role in the differential diagnosis of adenitis in non-immunocompromised children. OBJECTIVES: To describe the clinical and pathological findings in childhood NTMB adenitis and study the possible usefulness of antimicrobial therapy in addition to surgery. METHODS: We present eight cases of neck lymphadenitis occurring over a 5-year period. All of the children received combined chemotherapy, and six also underwent surgery. Of the two remaining patients, the parents of one child refused surgery and a watchful approach was adopted in the other. RESULTS: Complete clinical recovery was achieved in all patients except one who did not undergo surgery. CONCLUSIONS: Prolonged administration of two antibiotics (of which one must be clarithromycin) in addition to surgery was well-tolerated and could be useful in patients with NTMB neck lymphadenitis.
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