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  • Title: Morphology of mitochondria during apoptosis: worms-to-beetles in worms.
    Author: Youle RJ.
    Journal: Dev Cell; 2005 Mar; 8(3):298-9. PubMed ID: 15737923.
    Abstract:
    Although mitochondria are crucial for most pathways of mammalian cell apoptosis, evidence for their role in classic invertebrate models of programmed cell death has been frustratingly scant. New work showing that inhibition of mitochondrial fragmentation during C. elegans development inhibits programmed cell death bridges this gap and should advance a more detailed understanding of the role of mitochondria in caspase activation.
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