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  • Title: [Influence of blockades with local anesthetics on the stimulation ability of a nerve by peripheral nerve stimulation. Results of a randomized study].
    Author: Neuburger M, Gültlinger O, Ass B, Büttner J, Kaiser H.
    Journal: Anaesthesist; 2005 Jun; 54(6):575-7. PubMed ID: 15739091.
    Abstract:
    In the present study we examined the influence of local anesthetics on the ability to stimulate a nerve by means of peripheral nerve stimulation. In 35 patients either 5 ml saline (group 1, n=18) or local anesthetics (group 2, n=17) were injected close to the sciatic nerve in a randomized and double-blind manner. The current needed to stimulate the nerve was measured 30 s and 2 min after injection. The results showed that 30 s and 2 min after injection of local anesthetics there is a strong local anesthetic effect. Therefore nerve damage might occur despite the use of peripheral nerve stimulation. Thus, the multiple injection technique in a close anatomical area has to be considered critically, because anesthetized or partially anesthetized nerves have a lower stimulating ability and could be damaged by a second or third puncture.
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