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  • Title: Syringomyelia with Chiari malformation; 3 unusual cases with implications for pathogenesis.
    Author: Owler BK, Halmagyi GM, Brennan J, Besser M.
    Journal: Acta Neurochir (Wien); 2004 Oct; 146(10):1137-43; discussion 1143. PubMed ID: 15744850.
    Abstract:
    Syringomyelia is an important cause of neurological deficit. Most cases of non-traumatic syringomyelia occur in association with a Chiari malformation. We present three unusual examples of syringomyelia with such an association. The first case is that of syringomyelia in a young woman with Marfan's syndrome, a spontaneous CSF leak and intractable intracranial hypotension. The second is a woman with long-standing lumbo-peritoneal shunt for pseudotumour cerebri who developed an acquired Chiari malformation. A young woman with a Dandy-Walker cyst that herniated into the upper cervical canal is the third case. These cases provide a basis for discussion of the pathogenesis and management of syringomyelia and the Chiari malformation in such cases.
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