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  • Title: Biofilms and the plasmid maintenance question.
    Author: Imran M, Jones D, Smith H.
    Journal: Math Biosci; 2005 Feb; 193(2):183-204. PubMed ID: 15748729.
    Abstract:
    Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.
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