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  • Title: Preservation of hippocampal volume throughout adulthood in healthy men and women.
    Author: Sullivan EV, Marsh L, Pfefferbaum A.
    Journal: Neurobiol Aging; 2005 Jul; 26(7):1093-8. PubMed ID: 15748789.
    Abstract:
    To address controversies regarding the effect of age on the hippocampus, volumes of hippocampus and a comparison structure, temporal cortex, were measured on magnetic resonance imaging (MRI) in 84 healthy men and 44 healthy women (20-85 years). Neither men nor women showed significant correlations between hippocampal volumes and age, despite significant age-related decline in temporal volumes. Absence of hippocampus age relationships endured when restricting analyses to older individuals (> or =50 years) and considering menopause and hormone replacement therapy.
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