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  • Title: Tacrolimus ointment for the treatment of severe facial plaque psoriasis.
    Author: Kroft EB, Erceg A, Maimets K, Vissers W, van der Valk PG, van de Kerkhof PC.
    Journal: J Eur Acad Dermatol Venereol; 2005 Mar; 19(2):249-51. PubMed ID: 15752305.
    Abstract:
    Recently, tacrolimus ointment has proved to be effective and well tolerated in patients with facial psoriasis. A few months ago we had the opportunity to treat a patient with tacrolimus ointment who had severe and recalcitrant plaque psoriasis of the face. This present case illustrates the impressive improvement of facial plaque psoriasis following 5 months of treatment with tacrolimus 0.1% ointment twice a day. Significant improvement of facial plaque psoriasis was seen after 1 month and complete clearance after 5 months of therapy. Based on the available literature and illustrated by the present case we may conclude that tacrolimus ointment 0.1% can be recommended as a first-line treatment for facial psoriasis.
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