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  • Title: Rapidly progressive lung disease in a patient with cystic fibrosis on long-term azithromycin: possible role of mycoplasma infection.
    Author: Janahi IA, Abdulwahab A, Elshafie Sittana S, Bush A.
    Journal: J Cyst Fibros; 2005 Mar; 4(1):71-3. PubMed ID: 15752685.
    Abstract:
    Macrolides is effective therapy in patients with cystic fibrosis (CF). We describe a girl with CF given long-term azithromycin who died of rapidly progressive lung disease. She was found to have rising titers of mycoplasma serology, suggesting a possible causative role of a resistant mycoplasma infection. Mycoplasma infection should be considered in CF patients who are deteriorating, even if they are being treated with macrolides, to which these organisms are usually susceptible.
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