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  • Title: Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans.
    Author: Frank J, Kamal-Eldin A, Traber MG.
    Journal: Ann N Y Acad Sci; 2004 Dec; 1031():365-7. PubMed ID: 15753171.
    Abstract:
    Sesame seed and oil consumption previously increased human plasma gamma-tocopherol (gamma-T) concentrations. This was attributed to the sesame lignans sesamin and sesamolin. Here, we studied the inhibition of vitamin E metabolism by a single dose of sesame oil lignans coingested with deuterated alpha- and gamma-tocopherols in human volunteers. The urinary excretion of gamma-T metabolites was significantly lower in sesame oil treated than in control subjects. Concentrations of tocopherols in blood were not affected by the treatment. In conclusion, a single dose of sesame oil, containing 136 mg sesame lignans (sesamin and sesamolin), reduces the urinary excretion of co-administered gamma-T in humans.
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