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  • Title: Early aortic valve cusp rupture in relapsing polychondritis.
    Author: Marshall DA, Jackson R, Rae AP, Capell HA.
    Journal: Ann Rheum Dis; 1992 Mar; 51(3):413-5. PubMed ID: 1575597.
    Abstract:
    Aortic regurgitation associated with relapsing polychondritis usually occurs late in the disease as a result of aortic root dilatation. A case where aortic regurgitation occurred early and was due to cusp rupture with a normal aortic root is reported. The patient required urgent aortic valve replacement within six weeks of developing a murmur despite apparent control of inflammation with immunosuppressive treatment. The possibility of cusp rupture with sudden haemodynamic deterioration should be considered in patients with relapsing polychondritis who develop aortic regurgitation.
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