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  • Title: Molecular defects in the growth hormone-IGF axis.
    Author: Lee J, Menon RK.
    Journal: Indian J Pediatr; 2005 Feb; 72(2):145-8. PubMed ID: 15758538.
    Abstract:
    Many previously uncharacterized cases of poor growth in children, i.e. idiopathic short stature, are now attributable to genetic defects in the GH-IGF-1 axis. This paper will provide an overview of the clinical findings of patients identified with various genetic defects of the GH/IGF-1 axis with an emphasis on the more recently described syndromes.
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