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  • Title: Increasing erythromycin resistance among group A streptococci causing tonsillitis in a tertiary care hospital in southern India.
    Author: Brahmadathan KN, Anitha P, Gladstone P.
    Journal: Clin Microbiol Infect; 2005 Apr; 11(4):335-7. PubMed ID: 15760434.
    Abstract:
    Group A streptococci (GAS) (n = 1313) isolated from patients with clinical symptoms of pharyngitis or tonsillitis attending a tertiary care hospital in southern India during 1986-2002 were tested for susceptibility to penicillin and erythromycin. The overall erythromycin resistance rate was 2.7% (n = 36). During 1986-1993, erythromycin resistance was observed in only one (2%) isolate in 1987, but reappeared in 1994 (2.7%), increased to 5.8% in 1999, and reached a maximum frequency of 13.8% in 2002. All isolates were susceptible to penicillin. The data indicate the need for continued surveillance of susceptibility patterns among GAS isolates in order to monitor the development of antibiotic resistance.
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