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  • Title: [Risk factors of renal failure in the early post-liver transplantation period].
    Author: Zhu FX, Liu CJ, Zhu JY, Li GM, Huang L, Wang D, Gao J, Zheng ZM, Leng XS.
    Journal: Zhonghua Gan Zang Bing Za Zhi; 2005 Mar; 13(3):168-70. PubMed ID: 15760546.
    Abstract:
    OBJECTIVE: To study the risk factors of renal failure in the early post-liver transplantation period. METHODS: 92 consecutive liver transplantation cases were reviewed and a multi-factor analysis of presumed risk factors of early post-transplantation period renal failure was conducted. The factors analyzed were total bilirubin level, prothrombin activity, onset of structural renal disease, onset of gastrointestinal hemorrhage, whether the patient underwent large-volume paracentesis, or underwent plasmapheresis therapy, needed renal replacement therapy, the operation method used, the bleeding volume during operation and the immunosuppressive agents used. RESULTS: Of the 92 patients, 29 (31.5%) developed acute renal failure (ARF) in the early postoperative period. Multi-factor analysis revealed a high pre-transplantation serum creatinine level and low prothrombin activity as risk factors for development of ARF. CONCLUSION: ARF is a frequent medical complication after liver transplantation. A high pre-transplantation serum creatinine level and low prothrombin activity are risk factors of its development.
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