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  • Title: Polarity and motility of large polymer-actin complexes.
    Author: Kakugo A, Shikinaka K, Takekawa N, Sugimoto S, Osada Y, Gong JP.
    Journal: Biomacromolecules; 2005; 6(2):845-9. PubMed ID: 15762650.
    Abstract:
    The polarity of polymer-actin complexes obtained by mixing F-actin with synthetic polymers carrying positive charges such as poly(L-lysine), x,y-ionene bromide polymers, and poly(N-[3-(dimethylamino)propyl]acrylamide) (PDMAPAA-Q) have been investigated. Actin complexes formed with poly(L-lysine) and PDMAPAA-Q, which carry charges on their side chains, show a higher polarity than those formed with x,y-ionene bromide polymers, which have charges on their chain backbones. All these polymer-actin complex gels show motility on the surfaces coated with myosin by coupling to adenosine 5'-triphosphate hydrolysis. A linear correlation between the polarity of polymer-actin complex gels and the motility is observed.
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