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  • Title: [Two cases of urothelial cancer responsive to high-dose-intensity methotrexate vinblastine doxorubicin and cisplatin (M-VAC) therapy].
    Author: Fukuda H, Mitsumori K, Minagawa S, Kumazawa T, Tadachi K, Iinuma M, Satoh S, Satoh K, Habuchi T, Kato T.
    Journal: Hinyokika Kiyo; 2005 Feb; 51(2):113-6. PubMed ID: 15773365.
    Abstract:
    We report two cases of metastatic urothelial cancer treated with high-dose-intensity (HD) methotrexate vinblastine, doxorubicin and cisplatin (MVAC). After HD-MVAC, the size of primary and lymph node tumors decreased by 57-67% as compared with the standard M-VAC therapy. By shortening the dose interval, HD-MVAC may increase the anti-tumor effect without increasing side effects.
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