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  • Title: [Grzybowski type eruptive keratoacanthomas and ectropion. A therapeutic problem].
    Author: Laaff H, Mittelviefhaus H, Wokalek H, Schöpf E.
    Journal: Hautarzt; 1992 Mar; 43(3):143-7. PubMed ID: 1577602.
    Abstract:
    Eruptive Grzybowski-type keratoacanthoma is a rare variant of multiple keratoacanthoma and is not accompanied by internal malignancies. Up to now only 16 cases of eruptive Grzybowski-type keratoacanthoma have been described in the literature. Eruptive and solitary keratoacanthomas cannot be distinguished histologically. The multiplicity of skin lesions may be due to a genetic background. Our patient presented with multiple eruptive keratoacanthomas, ectropion and a mask-like face. Conservative treatment, e.g. with etretinate, did not lead to any improvement of symptoms in this case. Therefore surgical therapy was recommended for the patient's ectropion.
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