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  • Title: A new tetracycline antibiotic with antitumor activity. I. Taxonomy and fermentation of the producing strain, isolation and characterization of SF2575.
    Author: Hatsu M, Sasaki T, Watabe H, Miyadoh S, Nagasawa M, Shomura T, Sezaki M, Inouye S, Kondo S.
    Journal: J Antibiot (Tokyo); 1992 Mar; 45(3):320-4. PubMed ID: 1577660.
    Abstract:
    A new antitumor antibiotic SF2575 has been isolated from a culture filtrate of Streptomyces sp. SF2575. The molecular formula was determined to be C40H43NO15 by elemental analysis, mass and 13C NMR spectral analyses. The spectral data revealed SF2575 to be a new tetracycline antibiotic. It was active against Gram-positive bacteria and exhibited antitumor activity against P388 leukemia in mice.
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