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  • Title: Hemiparkinsonism and levodopa-induced dyskinesias after focal nigral lesion.
    Author: Růzicka E, Urgosík D, Jech R, Roth J, Vymazal J, Mecír P, Vladyka V.
    Journal: Mov Disord; 2005 Jun; 20(6):759-62. PubMed ID: 15782419.
    Abstract:
    We present a patient with tremor-dominant hemiparkinsonism after a focal lesion to the substantia nigra. An excellent response to levodopa was complicated by rapid development of motor fluctuations and disabling dyskinesias. Stereotactic thalamotomy resulted in a persistent extinction of parkinsonism and of dyskinesias along with stopping dopaminergic treatment.
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