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  • Title: Progressive supranuclear palsy-like phenotype associated with bilateral hypoxic-ischemic striopallidal lesions.
    Author: Kim HT, Shields S, Bhatia KP, Quinn N.
    Journal: Mov Disord; 2005 Jun; 20(6):755-7. PubMed ID: 15782420.
    Abstract:
    A progressive supranuclear palsy (PSP)-like syndrome due to vascular or anoxic brain insult is rare. We describe a 65-year-old man with a progressive PSP-like phenotype associated with hypoxic-ischemic bilateral striopallidal lesions, secondary to rupture of and subsequent surgery for a thoracic aortic aneurysm. After early extrapyramidal features, 10 months later he started to fall, and developed levator inhibition. A supranuclear gaze palsy for downgaze was documented 5.5 years after the insult.
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