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  • Title: Folate supplements prevent recurrence of neural tube defects.
    Journal: Nutr Rev; 1992 Jan; 50(1):22-4. PubMed ID: 1579267.
    Abstract:
    In a multicenter, randomized, double-blind intervention study, 4 mg of folate daily given around the time of conception significantly reduced the recurrence of neural tube defects. Supplementation with a folate-free multiple vitamin did not reduce the recurrence rate.
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