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  • Title: Mutant prevention concentrations of ABT-492, levofloxacin, moxifloxacin, and gatifloxacin against three common respiratory pathogens.
    Author: Hermsen ED, Hovde LB, Konstantinides GN, Rotschafer JC.
    Journal: Antimicrob Agents Chemother; 2005 Apr; 49(4):1633-5. PubMed ID: 15793158.
    Abstract:
    The purpose of this study was to compare the mutant prevention concentration (MPC) of ABT-492 to those of levofloxacin, moxifloxacin, and gatifloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. The fluoroquinolones had comparable mutation selection windows, which is the ratio of MPC/MIC, for all isolates.
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