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  • Title: [Magnetic resonance in the study of residual mediastinal masses after therapy of lymphoma].
    Author: Davini O, Levis A, Garabello D, Foggetti MD, Depaoli L, Cirillo R, De Lucchi R, Orsucci L, Resegotti L.
    Journal: Radiol Med; 1992 Mar; 83(3):230-6. PubMed ID: 1579671.
    Abstract:
    Forty-five patients with mediastinal spread of malignant, Hodgkin's and non-Hodgkin's lymphomas were examined with MR Imaging at 0.5 T. Ninety-two examinations were performed at diagnosis and/or during and after treatment to investigate MR capabilities in distinguishing fibrous tissue from active disease in the masses residuing after therapy--which cannot be done by means of CT. MR results indicated T2-weighted sequences to be the most useful. MR results were compared with the data collected from follow-up, clinics, and biology. MR Imaging had high accuracy (92.1%). The number of false negatives was very low, thanks to the low intensity of fibrous tissue, while a relatively high number of false positives was observed, probably due to the difficulties in discriminating inflammatory from neoplastic tissue.
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