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  • Title: Acute lung injury and bacterial infection.
    Author: Dreyfuss D, Ricard JD.
    Journal: Clin Chest Med; 2005 Mar; 26(1):105-12. PubMed ID: 15802172.
    Abstract:
    The relationships between acute lung injury and bacterial infection are complex. Indeed, sepsis and in particular pneumonia are leading causes of acute lung injury. Bacterial superinfection of the lung is a frequent complication of acute lung injury. Because of impaired host defenses and prolonged mechanical ventilation, more than one third of patients with the acute respiratory distress syndrome acquire ventilator-associated pneumonia, with resistant pathogens in most instances. This complication is responsible for more than a doubling of the time on mechanical ventilation but does not seem to increase mortality.
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