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  • Title: Diffuse normolipemic plane xanthoma in a 9-year-old boy.
    Author: Hofmann M, Zappel K, Trefzer U, Audring H, Albrecht-Nebe H, Sterry W, Blume-Peytavi U.
    Journal: Pediatr Dermatol; 2005; 22(2):127-9. PubMed ID: 15804300.
    Abstract:
    Normolipemic plane xanthoma normally occurs in adults. We report the atypical instance of a 9-year-old boy who developed disseminated, flat, yellow-brown plaques up to 2 to 3 cm without any complaints. The histology showed the hallmarks of xanthoma, including the presence of CD68+ foam cells and Touton giant cells. No systemic involvement or lipid disorders were evident. It is important to perform regular follow-up of these patients because normolipemic plane xanthoma often precedes myeloproliferative disorders such as leukemia, paraproteinemia, or lymphoma.
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