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  • Title: Genetics and the variability of treatment response in asthma.
    Author: Israel E.
    Journal: J Allergy Clin Immunol; 2005 Apr; 115(4 Suppl):S532-8. PubMed ID: 15806036.
    Abstract:
    Pharmacogenetics is the study of how genetic differences influence the variability in patients' responses to therapy. Using specific examples in asthma, I will define the concepts of variability in response to therapy in asthma. I will then use the relationship between specific genetic polymorphisms and the response to beta-adrenergic agonists and leukotriene modifiers to illustrate pharmacogenetic interactions and to acquaint the reader with the applicability of these findings to clinical practice.
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